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重要醫學知識—直系血親之間不要輸血

因部分朋友寫信來問此消息是否為真?所以寫Mail至馬偕 院詢問。


答案是"YES".


以下報告確實為馬偕醫院林媽利醫師所發表的,林媽利醫師目前是國內輸血醫學之個中翹楚。


輸血時許多人都不願意接受外來的血液,認為這可能會造成疾病的傳染。可是根據輸血專家的研究,如果體內輸入直系血親的血液,有極高機率引發移植物抗宿主疾病,而且發病後就無藥可解,死亡率達99%以上,是一項極危險的輸血行為。


第十屆國際輸血學會亞太大會今日在國際貿易會議中心舉辦,其中在國內常被忽略的近親輸血議題,在會場引發熱烈討論,馬偕醫院醫事檢驗科主任林媽利建議國內應停止直系血親輸血的行為。林媽利表示,由於遺傳因子的因素,如果父親血中含有雜合子!



他的父親、孩子血液(上、下一層)的直系親屬,血液中就含有純合子。 如果雜、純合子都以輸血方式,混合在人體內,這個人將有極高比例因組織抗原半型的因素,引發輸血後移植物抗宿主疾病,99%以上發病的人,平均會在輸血後的兩個月內死亡。



移植物抗宿主疾病的患者,多是因疾病或意外,才接受輸血。可是若體內再輸入與自己血液相左的純合子或雜合子,將使這個人免疫力更加降低,出現的反應有小疹子、貧血、腸胃、肺等臟器功能被破壞,患者會在短時間內死亡。



林媽利表示,一旦血液輸入到人體內,就會流竄至全身,根本無法再完全地抽取來,一旦引發輸血後移植物抗宿主疾病時,國內醫師只能束手無策,因為根本沒有藥物,可以去救這個人。而且當病人因血液純合子、雜合子混合,使免疫力下降時,很多病人甚至可能會被誤認為是因先前疾病所導致,隨著身體機能降 低、慢慢死亡。



至於輸入直系血親的血液,究竟有多少比例的人,會引發類似的抗宿主疾病,由於國內一直忽略近親輸血的高危險議題,有多少人因為捐輸親人血液而死,沒有類似的調查報告,但在日本先前至少已有5,600人確定是因被捐輸直系血親血液,引發不良反應而死亡。



若直系血親間捐、輸血,要避免引發移植物抗宿主疾病,就必須將血袋先經放射線的照射,以期破壞血液中的純合子或雜合子,可是因為太麻煩了,她還是建議民眾,接受捐血中心內非直系親屬的血袋,反而較為安全.



林媽利強調,國人還存有接受至親血液是最安全的錯誤觀念。


寄給別人看,以免終生遺憾!


Richard,  thank you for sharing.

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